Searchable abstracts of presentations at key conferences in endocrinology

ea0026p115 | Female reproduction | ECE2011

Injected FSH overriding ageing related elevated FSH through high activity of the hypothalomo-pituitary axis, enforces wanted multiple follicle growth in women undergoing IUI

Konig T E , Beemsterboer S N , Overbeek A , Hendriks M L , Heymans M W , Hompes P , Homburg R , Schats R , Lambalk C B

Introduction: The hypothalomo-pituitary response to the loss of ovarian function due to ageing is an increase in GnRH induced gonadothropic activity: FSH. It is thought that the pituitary gives maximum endogenous stimulation leading to FSH levels above the ovarian threshold to develop follicular growth and it is a matter of debate whether exogenous FSH (r-FSH) will or will not improve ovarian response. In intrauterine insemination (IUI) treatment r-FSH is used to induce multif...

ea0026p234 | Pituitary | ECE2011

Does GH replacement therapy reduce mortality in adults with GH deficiency? Data from the Dutch National Registry of GH Treatment in adults

van Bunderen C C , van Nieuwpoort I C , Arwert L I , Heymans M W , Franken A A M , Koppeschaar H P F , van der Lely A J , Drent M L

Introduction: Adults with GH deficiency (GHD) have a decreased life expectancy due to cardiovascular diseases (CVD). Recombinant GH treatment has made replacement therapy an option in adults with GHD. Data on long-term efficacy and safety are limited and the implication for life expectancy remains to be established.Methods: The Dutch National Registry of GH Treatment in Adults was founded to gain more insight into long-term efficacy and safety of GH ther...